Registration Dossier

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Study period:
09-1993
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: under GLP and complete

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1993
Report Date:
1993

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: EEC directive 84/449. Annex V, method C10.
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
reagent grade
Radiolabelling:
no

Study design

Analytical monitoring:
yes

Results and discussion

Dissipation half-life of parent compoundopen allclose all
pH:
4
Temp.:
50 °C
Hydrolysis rate constant:
0 s-1
Half-life:
676.7 h
pH:
4
Temp.:
80 °C
Hydrolysis rate constant:
0 s-1
Half-life:
78.1 h
pH:
4
Temp.:
90 °C
Hydrolysis rate constant:
0 s-1
Half-life:
41.9 h
pH:
7
Temp.:
25 °C
Hydrolysis rate constant:
0 s-1
Half-life:
68.5 h
pH:
7
Temp.:
50 °C
Hydrolysis rate constant:
0 s-1
Half-life:
6.1 h
pH:
9
Temp.:
50 °C
Half-life:
< 2.4 h

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
complete