Registration Dossier

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
March 1993
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: info on test material is not accordingly and test material concetnrations are based on nominal. Therefore the real concentration is unknown

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1993
Report Date:
1993

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: Method C1 of 84/449/EEC OECD Guideline 203
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
88% pure according to CoA

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
no
Details on test solutions:
Identity and concentration of auxiliary solvent for dispersal: None

Test organisms

Test organisms (species):
Oncorhynchus mykiss (previous name: Salmo gairdneri)

Study design

Test type:
semi-static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h

Test conditions

Hardness:
240 mg CaCO3/L
pH:
7.6-8.2
Dissolved oxygen:
97-100% of saturation
Nominal and measured concentrations:
nominal 62.5, 125, 250, 500, 1000 ug/L

Results and discussion

Effect concentrationsopen allclose all
Duration:
24 h
Dose descriptor:
LC50
Effect conc.:
0.4 mg/L
Basis for effect:
mortality
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
0.188 mg/L
Basis for effect:
mortality
Duration:
72 h
Dose descriptor:
LC50
Effect conc.:
0.188 mg/L
Basis for effect:
mortality
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
0.174 mg/L
Basis for effect:
mortality
Duration:
96 h
Dose descriptor:
NOEC
Effect conc.:
0.066 mg/L
Details on results:
%Concentration loss over test: 9 ... 26

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
Test is valid, however at the end the easured values are significantly lower then measured