Registration Dossier
Registration Dossier
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EC number: 249-854-8 | CAS number: 29797-40-8
Carcinogenicity
Administrative data
Description of key information
A carcinogenicity study is not available and has not been performed with dichlormethylbenzene and its isomers. In the in vitro and in vivo genotoxicty studies, dichloromethylbenzene was not mutagenic/genotoxic. Furthermore, in the available subchronic gavage study in Wistar rats as well as in the EOGRTS OECD 443 study no pathological or histopathological findings indicative for a neoplastic potential were observed.
Key value for chemical safety assessment
Justification for classification or non-classification
Based on the the available subchronic gavage study in Wistar rats as well as in the EOGRTS study and taking into account the absence of a genotoxic potential in the available in vitro and in vivo mutagenicity/genotoxicity tests, dichloromethylbenzene and its isomers is not considered to be a suspected carcinogen.
According to CLP classification criteria (Regulation (EC) No 1272/2008) a classification for carcinogenicity is not justified.
Additional information
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