Registration Dossier
Registration Dossier
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EC number: 249-854-8 | CAS number: 29797-40-8
Toxicity to terrestrial arthropods
Administrative data
- Endpoint:
- toxicity to terrestrial arthropods: long-term
- Data waiving:
- other justification
- Justification for data waiving:
- other:
- Justification for type of information:
- According to column 2 of REACH Annex IX, the equilibrium partitioning method can be applied to assess the hazard of soil organisms.
Based on REACH guidance document R7c, Table R7.11-2 (ECHA 2012), EPM can be applied if the substance is not highly adsorptive and/or not highly persistent in soil. Furthermore, the substance is not classified as very toxic Criteria according to Table R.7.11-2 Properties of Dichlormethylbenzene (mixture of isomers)
Highly adsorptive logKow > 5 logKow 4.2 - 4.3
Highly persistent DT50 in soil >180 d DT50 in soil ca. 90 - 120 d *
Very toxic to aquatic organisms EC/LC50 < 1 mg/L EC50 1.26 mg/L (lowest acute value) *
*The degradation in soil was determined in a non-guideline test under methanogenic conditions. The half life for the three main isomers 2,4-DCT, 2,5-DCT and 3,4-DCT was measured to about 90 days. The main isomers represent >80% of the whole isomeric mixture. The two minor isomers 2,3-DCT and 2,6-DCT are degraded slower, and no concrete half-life could be calculated. According to the graphs given in the publication a half-life of about 180 days for these 2 siomers can be estimated. The concentration of each of the 2 minor isomers is in the range up to 10%.
Taking all information into account a half-life for the whole substance of 90 to 120 days is estimated. Following REACH guidance document R7c, Table R7.11-2, performing of EPM is possible as long as the risk characterisation ratios are below 1. According to REACh Regulation (EC) No 1907/2006, Annex X, Column 2, tests on long-term toxicity to terrestrial organisms shall be proposed by the registrant if the results of the chemical safety assessment indicate the need to investigate further effects of the substance and/or relevant degradation products on terrestrial organisms. This is however not the case: The outcome of the CSA showed that all risk characterisation ratios in soil are below 1. For this reason, the performance of a test on the toxicity of dichloromethylbenzene for the terrestrial organisms is not needed.
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
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