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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2002
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Version / remarks:
- EEC Directive 92/69, A.8
Deviations:
not applicable
GLP compliance:
yes
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
4.1
Temp.:
25 °C
pH:
8.1
Remarks on result:
other: the pH value of the standard solution of 22.7 mg/100 mL methanol
Conclusions:
The partition coefficient of test substance was determined to be logPow= 4.1 at 25°C at pH 8.1
Executive summary:

In this guideline (OECD 117) study conducted to GLP standards, the test material (EC 438-340-0) was determined to have a partition coefficient logPow= 4.1 at 25°C at pH 8.1.

Description of key information

Study conducted to recognised testing guidelines with GLP.

Key value for chemical safety assessment

Log Kow (Log Pow):
4.1
at the temperature of:
25 °C

Additional information

logPow= 4.1 at 25°C at pH 8.1

The partition coefficient was performed by HPLC method