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Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Reference
Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2002
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 116 (Fat Solubility of Solid and Liquid Substances)
Version / remarks:
- EEC Directive 84/449, A.7, L251
Deviations:
not specified
GLP compliance:
yes
Medium:
standard fat
Remarks:
HB 307, batch 36
Solubility:
275.3 other: g/Kg fat
Temp.:
37 °C
Remarks on result:
other: ±4.3 g/Kg
Test substance stable:
yes
Conclusions:
The solubility of test substance in standard fat at 37°C was determined to be 275.3 g/kg
Executive summary:

In this guideline (OECD 116) study conducted to GLP standards, the test material (EC 438-340-0) was determined to have a solubility in standard fat of 275.3 g/kg at 37°C.

Description of key information

Study conducted to recognised testing guidelines with GLP.

Key value for chemical safety assessment

Solubility in mg/100g standard fat:
2.75
At the temperature of:
37 °C

Additional information

275 g/kg at 37°C in standard fat.