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EC number: 276-038-9
CAS number: 71808-53-2
The solvent (isopropanol) conceivably may
have played an indirect role in promoting the absorption of the active
ingredient through the skin, but it is unlikely that it directly
affected the percutaneoas toxicity to any great extent. On the basis of
active ingredient, the dose was 1. 68 g/kg. The dose of solvent
(isopropanol) given was 0.82 g/kg. This latter value is considerably
below the percutaneous LD50 for isopropanol (16. 4 ml/kg).
The product tested was applied to the skin
of rats for 24 hours at a dose of 2.5 g/kg. All animals dies within 48
to 56 hours. The dermal LD50 was less than 2.5 g/kg.
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