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EC number: 276-038-9
CAS number: 71808-53-2
The 96h LC50 of 2.40 mg/L (test material) was determined in an acute toxicity test with Danio rerio according to OECD TG 203 under GLP conditions (Reliability 2). The LC 50 = 1.84 mg/L based on the active ingredient concentration (76.7%).
Three acute fish toxicity studies are available for various
Quaternary ammonium compounds, alkylbis(hydroxyethyl)methyl, chlorides.
The key study is based on the same substance as registered: Quaternary
ammonium compounds, C12-18-alkylbis(hydroxyethyl)methyl, chlorides
(reliability 2). The two supporting studies are performed with pure
quaternary ammonium compound C12 and quaternary ammonium compound C14
(both reliability 4, because no GLP, no certificates of analysis of the
technical products were available, nominal concentrations based on test
material). All studies were performed according to OECD 203, only the
study performed with C12-18 was performed according to GLP criteria. The
study performed with the C12-18 will be used as key study.
The key study was performed with Danio rerio under
semi-static conditions in accordance with OECD TG 203 (GLP). The test
was assigned reliability 2 because no chemical analyses of the test
concentrations were performed during the test. The reported
concentrations are nominal concentrations based on test material
(76.7%). The LC50 (96 h) was calculated to be 2.40 mg/L with 98%
confidence limits of 1.8 and 3.2 mg/L. The LC50 converted to active
ingredient is 1.84 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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