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EC number: 806-509-1 | CAS number: 1393571-42-0
Concentration (% w/w) in acetone/
olive oil 4:1
No effects on bodyweight or clinical signs, except for mild redness of the ears at the highest concentration.
Exposure of 4 mice/ treatment during 3 consecutive days at the dorsal site of the ears with test substance (1, 2.5 or 5%) or vehicle. On day 6, 3H-methyl thymidine(20 μCi/mouse) was injected in the tail vein. Five hours thereafter mice were killed and draining auricular lymph nodes were pooled per dose group and assessed for 3HTdR after 18 hours incubation at 4°C using a Beckman LS6500 scintillation system.
At the highest dose tested the stimulation index was 5.15. The calculated EC3 is 3%. The test substance is considered sensitizing to the skin.
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