Registration Dossier

Administrative data

Link to relevant study record(s)

Description of key information

As no specific studies on absorption, distribution, metabolism and excretion are available, the physico-chemical properties of the substance or, where not available, for structurally related substances, and the results of available toxicity studies have been used to determine, as far as possible, a toxicokinetic profile for the substance “Reaction mass of l-Glutamic acid, N-coco acyl derivs., disodium salts and l-Glutamic acid, N-coco acyl derivs., monosodium salts”.
For risk assessment purposes the substance is considered to be completely absorbed following oral administration and inhalation exposure, and assumed to be absorbed at 25% following dermal exposure.
The different components of the substance are expected to be widely distributed, and mainly reutilised for other metabolic processes within the body.
Excretion of sodium and urea, resulting from catabolism of glutamic acid, will be excreted via the urine.

Key value for chemical safety assessment

Bioaccumulation potential:
no bioaccumulation potential
Absorption rate - oral (%):
100
Absorption rate - dermal (%):
25
Absorption rate - inhalation (%):
100

Additional information