Registration Dossier

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
review article or handbook
Title:
BG Chemie - Potential Health Hazards of Existing Chemiclas (TOXIKOLOGISCHE BEWERTUNG zu Benzolsulfonsäurehydrazid, BG-Nr. 220)
Author:
Berufsgenossenschaft Rohstoffe und chemische Industrie (BG RCI)

Materials and methods

GLP compliance:
not specified

Test animals

Species:
rabbit
Strain:
New Zealand White
Remarks:
male and female (3-4 kg)

Test system

Type of coverage:
other: using an adhesive dressing
Observation period:
7 days

Results and discussion

Any other information on results incl. tables

The treatment produced no skin changes of any kind.

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
Benzene sulphonic acid hydrazide was assessed as non-irritant (irritant value 0).