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Short-term toxicity to aquatic invertebrates

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Description of key information

The acute toxicity of Musk Ketone was tested on Daphnia magna, in accordance to method C.2 – Daphnia sp. Acute Immobilisation Test, Council Regulation (EC) No. 440/2008, published in O.J.L 142, 2008. The results of this experiment demonstrated that the EC50 is higher than the concentration 0.432 mg/L which is the measured concentration of saturated solution prepared from test item nominal concentration of 100 mg/L. The results: 48 hour EC50˃ 0.432 mg/L (measured initial concentration), 48 hour EC0= 0.432mg/L (measured initial concentration), 48 hour EC100 >0.432 mg/L (measured initial concentration).

Additional supporting study of the acute toxicity of Musk Ketone was also tested with Daphnia magna, in accordance to OECD Guidelines for Testing of Chemicals 202 ( Schramm et al, 1996). There was no toxic effect on daphnia at the highest concentration of the substance. The 48 hour EC50 was > 0.46mg/L.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
0.432 mg/L

Additional information