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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

The acute toxicity of Musk Ketone was tested on Daphnia magna, in accordance to method C.2 – Daphnia sp. Acute Immobilisation Test, Council Regulation (EC) No. 440/2008, published in O.J.L 142, 2008. The results of this experiment demonstrated that the EC50 is higher than the concentration 0.432 mg/L which is the measured concentration of saturated solution prepared from test item nominal concentration of 100 mg/L. The results: 48 hour EC50˃ 0.432 mg/L (measured initial concentration), 48 hour EC0= 0.432mg/L (measured initial concentration), 48 hour EC100 >0.432 mg/L (measured initial concentration).

Additional supporting study of the acute toxicity of Musk Ketone was also tested with Daphnia magna, in accordance to OECD Guidelines for Testing of Chemicals 202 ( Schramm et al, 1996). There was no toxic effect on daphnia at the highest concentration of the substance. The 48 hour EC50 was > 0.46mg/L.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
0.432 mg/L

Additional information