Registration Dossier

Physical & Chemical properties

Water solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Referenceopen allclose all

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Qualifier:
according to
Guideline:
other: no data
GLP compliance:
no
Key result
Water solubility:
0.029 other: mol/L
Temp.:
25 °C
Remarks on result:
other: converted: 3.543 g/L
Conclusions:
The solubility of 2,5-xylenol in water was determined spectrophotometrically at 25 °C as 0.029 mol/L.
Executive summary:

The solubility of 2,5-xylenol in water was determined spectrophotometrically at 25 °C as 0.029 mol/L.

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Qualifier:
according to
Guideline:
other: no data
GLP compliance:
no
Type of method:
other: colorimetric method and spectrophotometric method
Key result
Water solubility:
0.026 other: mol/L
Temp.:
25 °C
pH:
5.1
Remarks on result:
other: converted 3.176 g/L
Details on results:
For both methods, spectrophotometric method and colorimetric, the determination of solubility of 2,5-xylenol results in the same value.
Conclusions:
The solubility of 2,5-xylenol in water was determined to 0.026 mol/L (3.176 g/L) at 25 °C and a pH of 5.1.
Executive summary:

The solubility of 2,5-xylenol was measured with two different methods. Once photospectrometrically, once colorimetrically. The results derived from both determinations are the same: Solubility of 2,5-xylenol at 25 °C and a pH of 5.1 is 0.026 mol/L (3.176 g/L).

Endpoint:
water solubility
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: accepted calculation method
Qualifier:
according to
Guideline:
other: no data
GLP compliance:
no
Key result
Water solubility:
3.853 g/L
Temp.:
25 °C
Conclusions:
The water solubility of 2,5-xylenol was calculated as 3.853 g/mol at 25 °C.
Executive summary:

The water solubility of 2,5-xylenol was calculated as 3.853 g/mol at 25 °C.

Description of key information

The solubility of 2,5-xylenol in water was determined spectrophotometrically and colorimetrically at 25 °C and a pH of 5.1 as 0.026 mol/L.

Key value for chemical safety assessment

Water solubility:
3.176 g/L
at the temperature of:
25 °C

Additional information

The key value in g/L is converted from the puplished value 0.026 mol/L.

The values described in the supporting studies are in a similar range:

0.029 mol/L (3.543 g/mol) at 25 °C via spectrophotometrically method

3.853 g/mol, calculated with EpiSuite