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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Ecotoxicological Summary

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Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
5.2 µg/L
Assessment factor:
1 000
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
52 µg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.5 µg/L
Assessment factor:
10 000
Extrapolation method:
assessment factor
PNEC marine water (intermittent releases):
5 µg/L

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
11.96 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
0.195 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.019 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
0.036 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

Classification related key information

Biodegradation in water: under test conditions no biodegradation observed (2% after 28 d; OECD 301C)

Bioaccumulation in organisms: low potential (log Pow: 2.6, undissociated form; OECD TG 117, HPLC method)

 

Acute toxicity (freshwater):

- to Fish: LC50 (96 h): 5.7 mg/L (measured, initial)

- to aquatic invertebrates: EC50 (48 h): 5.2 mg/L (measured, initial)

- to Algae: ErC50(72 h): 29 mg/L (measured, initial)

 

Chronic toxicity (freshwater):

- to Fish: not available

- to aquatic invertebrates: not available

- to Algae:NOErC (72 h): 5 mg/L (measured, initial) 

Classification justification according to CLP

The substance 2,5-Xylenol (EC No 202-461-5) is listed on Annex VI of the Regulation (EC) No 1272/2008 (CLP Regulation). The harmonised classification and labelling for 2,5-Xylenol is Aquatic Chronic 2.
The harmonized classification is in line with the data listed above. 2,5-Xylenol is not readily biodegradable and has a low potential to bioaccumulate. The classification is based on the lowest acute effect concentration determined for aquatic invertebrates (EC50 (48 h): 5.2 mg/L) and the lack of rapid biodegradability. Based on the available data the self-classification for 2,5-Xylenol is Aquatic Chronic 2 according to the consolidated version of Regulation (EC) No 1272/2008 and further amendments (ATPs).