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EC number: 945-518-6
CAS number: -
The acute oral toxicity test was performed
on a similar substance 01 (read-across from supporting substance
-structural analogue or surrogate).
The Acute Toxic Class Method study was
carried out based on the guidelines described in: EC Commission
Directive 96/54/EC, Part B.1 tris “Acute Toxicity-Oral, Acute Toxic
Class Method" and OECD No 423, “Acute Oral Toxicity - Acute Toxic Class
The similar subtance was administered by
oral gavage to three Wistar rats of each sex at 2000 mg/kg body weight.
Animals were subjected to daily observations and weekly determination of
body weight. Macroscopic examination was performed after terminai
sacrifice (day 15). No mortality occurred. No clinical signs of systemic
toxicity were noted in any of the animals. Brown and/or black staining
of the neck and/or tail by the test substance was noted among the
animals during the study period. The body weight gain shown by the
animals over the study period was considered to be normal. No
abnormalities were found at macroscopic post mortem examination of the
animals. The oral LD50 value of the similar substance in Wistar rats was
established to exceed 2000 mg/kg body weight.
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