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EC number: 945-518-6
CAS number: -
The substance is an UVCB dark brown
powder with a characteristic odour.
In a DSC analysis showed
decomposition beginning at 278 °C.
Relative density was determined by
means of a pycnometer OECD 109 and the result value was D at 20 °C:
1.7927 at 20 °C.
Granulometry is of considerable
importance for the toxic properties of a substance as it influences
aspects such as: the route of exposure of humans and toxicity by
inhalation; the choice of route of administration for animal testing;
the efficiency of uptake in an organism; the distribution in the
environment. The substance presented a granulometry mass median
aerodynamic diameter (MMAD)= 108.9 µm.
<1% in volume of the test item has a
particle size <= 4 µm (respirable fraction (the mass fraction of
particles that reaches the alveoli).
The CEN document, EN 481 ‘Workplace
Atmospheres – size fraction definitions for measurement of airborne
particles’ (CEN 1993) provides definitions of the inhalable, thoracic
and respirable size fractions, and target specifications (conventions)
for sampling instruments to measure these fractions. The current
standard defines sampling conventions for particle size fractions which
are to be used in assessing the possible health effects resulting from
inhalation of airborne particles in the workplace. The different
particle sizes defined in EN 481 are:
- inhalable fraction (the mass
fraction of particles that can be inhaled by nose and mouth. Particles
>100 μm are not included in the inhalable convention; thoracic fraction
(the mass fraction of the inhaled particles that passes the larynx). The
convention for thoracic fraction sets that 50% of the particles in air
with an aerodynamic diameter of 10 μm belong to the thoracic fraction;
- respirable fraction (the mass
fraction of the inhaled particles that reaches the alveoli). The
convention for respirable fraction sets that 50% of particles with an
aerodynamic diameter of 4 μm belong to the respirable fraction.)
According to Annex VII of REACH
Regulation 1907/2006, column 2, the study of vapour pressure does not
need to be conducted for this substance but the lowest value accepted by
EUSES has been reported for a complete Risk assessment (0.0000001 Pa).
Partition coefficient was determined
in HPLC and was stated as < 0.3 (log Pow). The tested substance is
considered very soluble (73.16 ± 3.47 g/L).
to Annex VII of REACH Regulation 1907/2006, column 2 no surface activity
is expected or can be predicted; therefore the testing can be waived. As
solid, the substance has no a flash point and the test can also be
is not expected to be auto-flammable, flammable, explosive and it is
deemed to be potentially not oxidising based on the chemical structure,
the oxygen balance values and the known experience in the handling and
use of the substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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