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EC number: 701-083-2
CAS number: -
Two male and female fasted rats were dosed with liquid boron 135g/L at
2000 mg/Kg on day 1. The test article was dispered in purified water at
a concentration of 10% m/v and administered by oral lavage at a dose
volume of 20 mL/Kg. All animals were killed on Day 8 and subsequently
underwent a terminal macrosopic examination.
No animal died. There were no clinical signs of of systemic toxicity.
All rats made substantial body weight gains between day 1 and day 8. No
macroscopic changes were apparent at necroscopy on day 8.
Single oral administration of liquid boron 135 g/L to a group of four
fasted rats at a dose level of 2000 mg/kg had no adverse effects.
Accordingly, the acute median lethal oral dose and the minmum lethal
oral dose to rats was shown to exceed 2000mg/kg bodyweight.
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