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Environmental fate & pathways

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Description of key information

Bioaccumulation: aquatic/sediment

Using Bio-concentration Factor (v12.1.0.50374) module ACD (Advanced Chemistry Development)/I-Lab predictive module, 2017), Bio-concentration Factor of the test substance 1,5-bis(cyclohexylamino)-9,10-dihydroanthracene-9,10-dione was estimated to be 13.2, 105, 3163, 20186,  31556, 33340, 33528, 33547 and 33549 at pH range 0, 1, 2, 3, 4, 5, 6, 7 and 8-14, respectively. This value indicates that the test substance 1,5-bis(cyclohexylamino)-9,10-dihydroanthracene-9,10-dione was considered to be very bioaccumulative in aquatic organisms.

Additional information

Bioaccumulation: aquatic/sediment

Various predicted data for the target compound 1,5-bis(cyclohexylamino)-9,10-dihydroanthracene-9,10-dione (CAS No. 15958-68-6) were reviewed for the bioaccumulation end point which are summarized as below:

 

In a prediction done byUsing Bio-concentration Factor (v12.1.0.50374) moduleACD (Advanced Chemistry Development)/I-Lab predictive module, 2017), theBCF of the test substance 1,5-bis(cyclohexylamino)-9,10-dihydroanthracene-9,10-dione was estimated to be 13.2, 105, 3163, 20186,  31556, 33340, 33528, 33547 and 33549 at pH range 0, 1, 2, 3, 4, 5, 6, 7 and 8-14, respectively. This value indicates that the test substance 1,5-bis(cyclohexylamino)-9,10-dihydroanthracene-9,10-dione was considered to be very bioaccumulative in aquatic organisms.

 

Bioconcentration Factor (BCF) of test chemical 1,5-bis(cyclohexylamino)-9,10-dihydroanthracene-9,10-dione (CAS no.15958 -68 -6) as estimated using Chemspider database(ChemSpider, 2017). The bioconcentration factor of test substance 1,5-bis(cyclohexylamino)-9,10-dihydroanthracene-9,10-dione was estimated to be 16936.89 at pH 5.5 and 16970.10 at pH 7.4, respectively, which exceeds the bioconcentration threshold of 5000, indicating that the chemical 1,5 -bis(cyclohexylamino)-9,10 -dihydroanthracene-9,10 -dione is expected to very bioaccumulative in the food chain.

 

Another predicted data was estimated usingSciFinder database (American Chemical Society (ACS), 2017) was used for predicting the bioconcentration factor (BCF) of test chemical 1,5 -bis(cyclohexylamino)-9,10 -dihydroanthracene-9,10 -dione (CAS No. 15958 -68 -6). The bioconcentration factor (BCF) of 1,5-bis(cyclohexylamino)-9,10-dihydroanthracene-9,10-dione was estimated to be 351, 10500, 67200, 105000, 111000 and 112000 at pH range 0, 1, 2, 3, 4, 5 and 6-10, respectively (at 25 deg C) which exceeds the bioconcentration threshold of 5000, indicating that the chemical 1,5-bis(cyclohexylamino)-9,10-dihydroanthracene-9,10-dione is  expected to very bioaccumulative in the food chain.

 

On the basis of above results for target chemical1,5-bis(cyclohexylamino)-9,10-dihydroanthracene-9,10-dione(from ACD labs,ChemSpider and SciFinder database,  2017), it can be concluded that the BCF value of test substance1,5-bis(cyclohexylamino)-9,10-dihydroanthracene-9,10-dione ranges from 13.2 –112000which exceeds the bioconcentration threshold of 5000, indicating that the chemical 1,5-bis(cyclohexylamino)-9,10-dihydroanthracene-9,10-dione is expected to be very bioaccumulative in the food chain.