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Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
17-07-2017 – 21-07-2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
Experimental test result performed using standard test guidelines
Qualifier:
according to
Guideline:
other: spectrophotometric analytical method
Principles of method if other than guideline:
The water solubility determination of test item 1,4-Dichloro-2-nitrobenzene was done as per the OECD guideline 105 by spectrophotometric analytical method as per OECD 101.
GLP compliance:
no
Type of method:
other: spectrophotometric analytical method
Specific details on test material used for the study:
Details on test material
- Name of test material (as cited in study report): 2,5-Dichloronitrobenzene
- Molecular formula (if other than submission substance): C6-H3-Cl2-N-O2
- Molecular weight (if other than submission substance): 192.001
- Smiles notation (if other than submission substance): c1(c(ccc(c1)Cl)Cl)[N+](=O)[O-]
- InChl (if other than submission substance): 1S/C6H3Cl2NO2/c7-4-1-2-5(8)6(3-4)9(10)11/h1-3H
- Structural formula attached as image file (if other than submission substance): see Fig.
- Substance type:Organic
- Physical state:Solid
Key result
Water solubility:
84.095 mg/L
Conc. based on:
test mat.
Incubation duration:
72 h
Temp.:
25 °C
Remarks on result:
other: No other detail available

Obseravtionn Table:

Sample stirring

Concentration obtained on

Dilution factor

Solubility value obtained

 

the basis of standard curve

 

(mg/L)

24 hour

-

-

-

48 hour

7.759 mg/L

10

77.59 mg/L

72 hour

9.060 mg/L

10

90.6 mg/L

Conclusions:
The water solubility determination of test item 1,4-Dichloro-2-nitrobenzene was done by spectrophotometric method. The water solubility was determine to be 84.095 mg/L at 25°C.
Executive summary:

The water solubility determination of test item 1,4-Dichloro-2-nitrobenzene was done as per the OECD guideline 105 byspectrophotometric analytical method as per OECD 101. The water solubility was determine to be 84.095 mg/L at 25°C.

Thus the chemical 1,4-Dichloro-2-nitrobenzene (CAS No. 89 -61 -2) is considered to be slightly soluble.

Description of key information

The water solubility determination of test item 1,4-Dichloro-2-nitrobenzene was done as per the OECD guideline 105 by spectrophotometric analytical method as per OECD 101. The water solubility was determined to be 84.095 mg/L at 25°C. Thus the chemical 1,4-Dichloro-2-nitrobenzene (CAS No. 89 -61 -2) is considered to be slightly soluble.

Key value for chemical safety assessment

Water solubility:
84.095 mg/L

Additional information

The water solubility determination of test item 1,4-Dichloro-2-nitrobenzene was done as per the OECD guideline 105 by spectrophotometric analytical method as per OECD 101. The water solubility was determined to be 84.095 mg/L at 25°C. Thus the chemical 1,4-Dichloro-2-nitrobenzene (CAS No. 89 -61 -2) is considered to be slightly soluble.

The water solubility of chemical 1,4-dichloro-2-nitrobenzene is determine to be 83 mg/L at 20 deg C. Thus chemical consider to be slightly soluble.

Thus based on the above both studies from experimental study report and other database, chemical consider to be slightly soluble.