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Description of key information

Determination of the Adsorption coefficient of p-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline (496981)
(GLP compliant study based on the Commission Regulation (EC) No 440/2008, C19, 2008 and OECD No. 121, 2001)
Author: Dr. Ir. E. Baltussen

Key value for chemical safety assessment

Koc at 20 °C:

Additional information

The Adsorption coefficient of p-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline was determined according to OCDE and EC Guidelines, which gives internationally accepted methods.

The HPLC method using soil-adsorption-reference data was applied for the determination of the adsorption coefficient (Koc) of the test substance. The Koc and log Koc value of the test substance and impurities with peak areas > 1% at neutral pH was :

Koc  log Koc  Area (%)
Test substance  84 1.93 96
Impurity III 50 1.7 1.1

This study is classified acceptable and satisfies the guideline requirements for Adsorption coefficient studies.

[LogKoc: 1.93]