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EC number: 225-716-2
CAS number: 5026-74-4
The half life in water has been determined to be 10.8 days according to
the DT50 values taken from OECD 309 Aerobic Mineralisation testing in
surface water. After 59 days, the degraded to 8 major unidentified
degradates; polar material and unknowns. Tentative identification of
four hyrolysis products and their oxidised forms was made.
Hydrolysis of p-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline was
studied at 20, 40 and 50 ºC in sterile aqueous buffered solutions at pH
4, pH 7 and pH 9. The hydrolysis at 25oC was estimated based on the
Regarding the biodegradation, the test item was not considered readily
biodegradable under the conditions of the modified strum test performed.
With regard to the read across, neither the p- or m- isomer are
considered readily biodegradable in OECD 301F or OECD 301B,
p-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline was only degraded
up to 4% within 28 days and the m-isomer substance up to 11%. The
m-isomer, in an OECD 302 B study, was not considered to be inherently
OECD 309 Aerobic Mineralisation study was
conducted to simulate potential for ultimate degradation in surface
water. Total recoveries of radioactivity (mass balances) for samples
treated at 10 μg/L and 100 μg/L were between 97.3 and 110.0% applied
radioactivity. Carbon dioxide accounted for a maximum of 15.0% applied
radioactivity. After 59 days
p-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl) aniline accounted for 1.0
to 3.8% applied radioactivity. DT50 values of 10.2 days and 11.4 days
were recorded for concentrations of 10ug/L and 100 ug/L respectively.
of the surface water samples showed that
aniline degraded to 8 major unidentified degradates; polar material and
1, 3, 7, 10, 13, 14 and 17, accounting for maximums of 16.8, 11.7, 31.4,
10.2, 12.3, 11.9, 9.4 and 13.1% applied radioactivity, respectively.All
other (unidentified) degradation products were present at levels of
Tentative identification of four hydrolysis products and their oxidised
forms was made.
The biodegradation in soil was waived in accordance with column 2 of
REACh (Regulation (EC) No 1907/2006) Annex IX, the soil simulation
testing (required in section 220.127.116.11) does not need to be conducted as
direct and indirect exposure of soil is unlikely.
In accordance with column 2 of REACh (Regulation (EC) No 1907/2006)
Annex IX, the sediment simulation testing (required in section 18.104.22.168,
and 22.214.171.124) do not need to be conducted based on the findings of the
Chemical Safety Assessment; the substance does not fulfil classification
criteria according to the applicable regulations and does not fulfil the
criteria for vPvB or PBT.
The adsorption coefficient was found to be, Log Koc = 1.93 at 20oC. The
substance is slightly moblie (according to Guth mobility classification,
1985) and the substance is expected to have a low potential for
bioaccumulation as it has a low octanol-water partition coefficient (Log
Pow = 0.87)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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