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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to other aquatic organisms

Currently viewing:

Administrative data

Endpoint:
toxicity to other aquatic vertebrates
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data from reliable database

Data source

Reference
Title:
No information
Author:
Dumpert K (1987). Embryonic effects of environmental chemicals: tests with the South African clawed toad (Xenopus laevis). Ecotox Environ Safety 13: 324-338.||cited in:|GDCh (1997). BUA Report 171: Aniline (Aug 1995). Advisory|Committee on Existing Chemicals of Environmental Relevance. |S. Hirzel, Stuttgart, Germany.

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Aniline
EC Number:
200-539-3
EC Name:
Aniline
Cas Number:
62-53-3
Molecular formula:
C6H7N
IUPAC Name:
aniline

Test organisms

Test organisms (species):
Xenopus laevis

Results and discussion

Any other information on results incl. tables

RS-Freetext:
test 1: tadpoles (larvae)
test conc.
   survival time
(mg/l)
    1        > 14 d
   10        > 14 d
  100        ca. 10 d
 1000        ca.  2 d
10000
        30 sec
 
test 2: tadpoles (larvae)
test conc.
   survival time/comments
(mg/l)
 10          development of toads
 30          development of toads
 50, 70, 80  development severely retarded; little
             pigmentation, no toads survived
 90          max. 12 d
100
          max. 12 d
 
test 3: embryos eggs
test conc.
   comments
(mg/l)
1-40
         concentration-dependent retardation 
             of larval development
  1          significant reatrdation of embryogenesis 
             and reduced survival
 30           5 +- 5 % mortality
 40          15 +- 10 % mortality

Applicant's summary and conclusion