Registration Dossier
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EC number: 203-581-0 | CAS number: 108-42-9
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
The lethal concentration (LC50) of 3-chloroaniline in soil macroorganism (Allolobophora tuberculata) in a short term study of 48 hrs study on the basis of mortality effect was estimated to be 169.22 mg/kg soil dw.
Key value for chemical safety assessment
- Short-term EC50 or LC50 for soil macroorganisms:
- 169.22 mg/kg soil dw
Additional information
No. of studies were reviewed for toxicity to soil macroorganisms except arthropods from reliable sources having Klimisch rating 2 and 4.
The summary of the results are presented below
Sr.No |
Endpoint |
Effect values |
Basis for effects |
Duration |
Species |
Sources |
1 |
LC50 |
169.22 mg/kg soil dw |
Mortality |
48 hrs |
Allolobophora tuberculata |
Predicted data from QSAr for CAS : 108-42-9 |
2 |
EC50 |
90-270 mg/kg soil dw |
Reproduction |
56 days |
Eisenia fetida |
Experimental data from J. Soils Sediments for RA CAS : 95-76-1 |
Based on the studies summarized in the above table for the target substance 3-chloroaniline and the read across substance 3,4-dichloroaniline in a soil macroorganisms (Allolobophora tuberculata and Eisenia fetida),the endpoint value was found to vary between the lethal concentration (LC50) = 169.22 mg/kg soil dw and effective concentration (EC50) = 90-270 mg/kg soil dw in a 48 hrs study to 21 days study on the basis of mortality and reproduction effect.
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