Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-852-0 | CAS number: 100-43-6
Toxicity to birds
Administrative data
Link to relevant study record(s)
Description of key information
Toxicity testing of 4-vinylpyridine (4VP) to birds was waived. In accordance with Regulation (EC) No.1907/2006, Annex X, Column 2, studies on the effects of the substance upon birds need not be conducted if direct and indirect exposure to the soil compartment is unlikely. Direct releases of 4VP to soil were not predicted in the exposure scenarios. Deposition of 4VP in soils from atmospheric deposition is expected to be limited, considering the short half-life of 4VP in air due to reaction with atmospheric free radicals (i.e., hydroxyl, nitrate and ozone radicals). Any 4VP that is released to soils is unlikely to be distributed to the soil compartment. The log Koc for 4VP is 2.3414; this value falls within the range of log Koc values (1.5 to 2.5) which indicate that the compound does not have the potential to sorb strongly onto sediment or soil. Therefore, direct or indirect exposure of soil to 4VP in soils is unlikely. Evaluation of upper trophic level exposures (secondary poisoning) is not of concern since 4VP is not lipophilic or bioaccumulative, based on log Kow of 1.36, a BCF in the range of 48-96, and a solubility of 29100 mg/l , and does not meet the criteria for bioaccumulative (log Kow > 3, BCF > 100) in section B.7.2.7 of Hazard Assessment, Part B of Guidance on information requirements and chemical safety assessment (ECHA, May 2008, pp. 45-46).
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
