Zeolite, cuboidal, crystalline, synthetic, non fibrous, thermally produced

Long-term toxicity to fish

Administrative data

Endpoint:

fish short-term toxicity test on embryo and sac-fry stages

Type of information:

migrated information: read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Test procedure is in accordance with national standard methods with acceptable restrictions (no GLP).

Data source

Reference

Reference 1

Reference Type:

publication

Title:

Aquatic environmental safety assessment for a nonphosphate detergent builder.

Author:

Maki AW and Macek KJ

Year:

1978

Bibliographic source:

Environ. Sci. Technol. 12, 573-580.

Reference 2

Reference Type:

publication

Title:

Correlations between Daphnia magna and fathead minnow (Pimephales promelas) chronic toxicity values for several classes of test substances.

Author:

Maki AW

Year:

1979

Bibliographic source:

J. Fish. Res. Board Can. 36, 411-421.

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: U.S. Environmental Protection Agency, Proposed recommended bioassay procedures for egg and fry stages of freshwater fish, Duluth, Minn., 1972

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

Automatically generated during migration to IUCLID 6, no data available

IUPAC Name:

Automatically generated during migration to IUCLID 6, no data available

Details on test material:

- Name of test material (as cited in study report): Type A zeolite
- Chemical name: Zeolite, cuboidal, crystalline, synthetic, non-fibrous
- Framework: cuboidal
- Related CAS number: 1318-02-1
- Analytical purity: no data
- Type A zeolite was surface modified: Analysis by atomic adsorption indicated that 90% existed in the Ca2+-modified form with a total of 10% as Mg2+, Na+ and K+ salts.

Sampling and analysis

Analytical monitoring:

yes

Test solutions

Vehicle:

no

Details on test solutions:

- Analysis by the silicate method (APHA 1977)

Test organisms

Test organisms (species):

Pimephales promelas

Study design

Test type:

flow-through

Water media type:

freshwater

Limit test:

no

Total exposure duration:

30 d

Test conditions

Hardness:

36 mg/L CaCO3

Test temperature:

no data

pH:

pH 7.6 +/- 0.3

Dissolved oxygen:

> 86% saturation

Nominal and measured concentrations:

0, 6.2, 12.3, 22.6 and 86.7 mg/L (mean measured concentrations).

Results and discussion

Effect concentrations

Duration:

30 d

Dose descriptor:

NOEC

Effect conc.:

> 86.7 mg/L

Nominal / measured:

meas. (not specified)

Conc. based on:

test mat.

Basis for effect:

other: hatch, survival, mean total length, average weight

Any other information on results incl. tables

The results indicate no adverse effects on hatchability of eggs and survival, mean total length, and average weight of fry at 30 days post hatch during all exposures to zeolite A.
The concentrations of test materials in suspension varied considerably during the exposure period, reflecting the difficulty of maintaining uniform suspensions of these particulates. Highest zeolite concentrations varied from 33 to 182 mg/L with a mean of 87 mg/L. Thus, the observed NOEC was determined to be greater than this value.