Registration Dossier

Administrative data

Endpoint:
toxicity to other aquatic vertebrates
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Basic data are given, the study meets basic scientific principles

Data source

Reference
Reference Type:
publication
Title:
Substitutes for phosphate containing washing products: their toxicity and biodegradability in the aquatic environment
Author:
Canton JH and Sloof W
Year:
1982
Bibliographic source:
Chemosphere 11, 891-907

Materials and methods

GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): NAS-a, code synthetic zeolite type 4A*
- Specification: loss on ignition 19.6%, 35.3% Al2O3, 42.0% SiO2, 22.3% Na2O, 600 mg/kg Ca, 210 mg/kg Fe, < 10 mg/kg heavy metals
- surface modified with Ca
- Chemical name: Zeolite, cuboidal, crystalline, synthetic, non-fibrous
- Framework: cuboidal
- Related CAS No. 1318-02-1
and
- Name of test material (as cited in study report): NAS-b, code synthetic zeolite type NaA
- Specification: 28% Al2O3, 33% SiO2, 17% Na2O, 22% H20, <150 mg/kg Fe, <3 mg/kg As, < 10 mg/kg heavy metals as Pb
- surface modified with Ca
- Chemical name: Zeolite, cuboidal, crystalline, synthetic, non-fibrous
- Framework: cuboidal
- Related CAS No. 1318-02-1

*sample tested was a precursor with sharp crystal structure

Test organisms

Test organisms (species):
Xenopus laevis

Study design

Test type:
semi-static
Water media type:
freshwater
Total exposure duration:
96 h

Results and discussion

Effect concentrations
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
1 800 - 3 200 mg/L
Basis for effect:
mortality

Any other information on results incl. tables

The LC50 values were observed in the range of 1800 - 3200 mg/L. When the test solutions were corrected for pH and oxygen content, LC50 values were observed between 5600 and 10000 mg/L.

Applicant's summary and conclusion