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Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Study period:
March 23, 2006 - July 17, 2006
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2006
Report date:
2003

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
2-methyl-4-oxo-3-(prop-2-en-1-yl)cyclopent-2-en-1-yl (1R)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate
EC Number:
687-634-7
Cas Number:
231937-89-6
Molecular formula:
C19H26O3
IUPAC Name:
2-methyl-4-oxo-3-(prop-2-en-1-yl)cyclopent-2-en-1-yl (1R)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate
Test material form:
liquid: viscous

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
yes

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
static
Total exposure duration:
48 h

Test conditions

Hardness:
2.5 mmol/L
Test temperature:
20+/-2 °C
pH:
7.27 - 8.71
Dissolved oxygen:
oxygen saturation
Salinity:
0.8 mmol/L
Nominal and measured concentrations:
20, 36, 64, 112 and 200 microg/l - nominal
5, 7, 11.1, 29.7, 60.2 microg/l - measured (mean)

Results and discussion

Effect concentrationsopen allclose all
Key result
Duration:
48 h
Dose descriptor:
NOEC
Effect conc.:
5 µg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
other: immobilization
Key result
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
6.1 µg/L
95% CI:
18.7 - 65.2
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
other: immobilization

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
Under semi-static conditions, calculated based on the mean of the measured exposure concentrations : 48 h LC50 = 6.1 microg/L, 48 h NOEC = 5.0 microg/L
Executive summary:

Juvenile daphnids were exposed in a static test to an aqueous test medium containing the test item at five nominal concentrations under defined conditions. The exposed organisms were checked for immobilization 24 and 48 h after test initiation. The actual tests concentrations were analytically measured.