Registration Dossier
Registration Dossier
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Reaction mass of 5,5'-{(phenylmethanediyl)bis[benzene-4,1-diyl-diazene-2,1-diyl]}bis{1-[3-(dimethylamino)propyl]-4-methyl-6-oxo-3-(pyridinium-1-yl)-1,6-dihydropyridin-2-olate} hydrochloride and 5,5’-[3,4’-(phenylmethanediyl)diphenylene]bis(diazene-2,1-diyl)bis{1-[3-(dimethylamino)propyl]-4-methyl-6-oxo-3-(pyridinium-1-yl)-1,6-dihydropyridin-2-olate} hydrochloride
EC number: 700-312-3 | CAS number: -
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The substance registered has a short-term algae toxicity EC50 growth rate of 1.76 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 1.76 mg/L
Additional information
A valid short-term algal growth inhibition study was conducted in the year 2008 on the analogue substance. The applicability of the read across approach had been confirmed by the registrant via an expert statement (see IUCLID chapter 13).
The 72‑hour EC50 of the analogue substance was calculated to be 1.8 mg/L for growth (which is the preferred parameter for classification purposes).
Given the applicability of the proposed read across approach, and based on the same molarity, for the substance registered the resulting EC50 growth rate is 1.76 mg/L and the NOEC 0.48 mg/L. These results basically were being confirmed by a study on the substance registered itself, with an estimated EC50 growth rate 1 - 10 mg/L, and an estimated NOEC < 1 mg/L.The result supports the classification of the substance registered as toxic to the aquatic environment.
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