Registration Dossier
Registration Dossier
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Reaction mass of 5,5'-{(phenylmethanediyl)bis[benzene-4,1-diyl-diazene-2,1-diyl]}bis{1-[3-(dimethylamino)propyl]-4-methyl-6-oxo-3-(pyridinium-1-yl)-1,6-dihydropyridin-2-olate} hydrochloride and 5,5’-[3,4’-(phenylmethanediyl)diphenylene]bis(diazene-2,1-diyl)bis{1-[3-(dimethylamino)propyl]-4-methyl-6-oxo-3-(pyridinium-1-yl)-1,6-dihydropyridin-2-olate} hydrochloride
EC number: 700-312-3 | CAS number: -
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The substance registered has an acute fish toxicity LC50 of 1.66 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 1.66 mg/L
Additional information
A valid short-term fish toxicity study was conducted in the year 2008 on the analogue substance.
The applicability of the read across approach had been confirmed by the registrant via an expert statement (see IUCLID chapter 13).
The 96‑hour LC50 of the analogue substance was calculated to be 1.7 mg/L with a 95% confidence interval of 0.5-6.3 mg/L.
Based on the same molarity, for the substance registered the resulting LC50 was 1.66 mg/L.This result basically was being confirmed by a non-key study with the substance registered (estimated LC50 = 1 - 10 mg/L).
The result supports the classification of the substance registered as toxic to the aquatic environment.
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