Registration Dossier

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:
Methyl 3-α,7-α-diacetoxy-12-α-hydroxy-5-β-cholan-24-oate is NOT a SKIN SENSITIZER.

Justification for selection of skin sensitisation endpoint:
Tools involved in the prediction are two validated profilers relevant for skin sensitization.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification

Based on the results of a QSAR prediction, methyl 3-α,7-α-diacetoxy-12-α-hydroxy-5-β-cholan-24-oate is not classified for skin seinsitization, according to Regulation 1272/2008/EC.