Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2012
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report Date:
2012

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
no
Type of method:
column elution method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: white solid
Details on test material:
Batch 2237 JG; expiry date June 2012

Results and discussion

Water solubility
Water solubility:
< 2.5 mg/L
Temp.:
20 °C
pH:
ca. 6
Details on results:
Concentration of APG in all samples was found < 2.5 mg/L.

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): other: water solubility < 2.5 mg/L
Water solubility of 2237 JG < 2.5 mg/L (OECD guideline 105 - column elution method)
Executive summary:

The water solubility of 2237 JG was determined following the column elution method (OECD guideline 105).

A 100 mg/L solution of test item in methanol was loaded on the column filled with glass beads and the column was dried. The test item was eluted with deionised water. This test was realised with a flow of 25 mL/h and 12.5 mL/h. Samples were analysed were analysed for APG by GC-FID.

At both flows, all samples were quantified < 0.25 mg/L of APG.

This leads to the conclusion that 2237 JG has a water solubility < 2.5 mg/L (APG).