Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Study period:
March 2008 to July 2008
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2011
Report Date:
2011

Materials and methods

Test guideline
Qualifier:
no guideline required
Deviations:
no
Principles of method if other than guideline:
The partition coefficient is defined as the ratio of the equilibrium concentrations of the test substance in a two-phase system consisting of two largely immiscible solvents.
The methods given in the Commission Directive 92/69/EEC, Commission Regulation (EC) No. 440/2008 – EC A8 Method (2008) are not usable when the substance shows tension-active properties which is presumably the case for 2237JG.
Therefore, the logKow of the test item is derived using a calculation method. The software EpiSuite was used for this calculation.
GLP compliance:
yes
Type of method:
other:
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
ca. 7.7
Temp.:
20 °C
Details on results:
The log P of the substance is defined as the highest value of the log P of the constituents of the test item.

Any other information on results incl. tables

 Substances contained in 2237JG  Value of log Pow
1,12-octadecanediol  6.6
1,12-octadecanediolmonoglucoside  2.8
octadecanol  7.7

Applicant's summary and conclusion

Conclusions:
The log P of the test item is equal to 7.7
Executive summary:

The log P of the test item is equal to 7.7