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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

The 96-h LC50 value of AC-6000 in the freshwater fish Oryzias latipes is > 10 mg/L; this value will be used in the assessment.

Key value for chemical safety assessment

Additional information

A GLP-compliant OECD 203 guideline study with Japanese killifish (Oryzias latipes) is available for AC-6000 (Kurume Laboratory, 2006b). Fish (10/dose) were exposed to nominal concentrations of 10 mg/L under semi-static conditions for 96 hours; the test concentrations were not analytically verified. No information is available with regard to mortality in the controls and the test concentration, the 96-h LC50 value is >10 mg/L.

Another study with freshwater fish is available, but as the study is in Japanese it currently cannot be taken into account. The 96-h LC50 value is >0.145 mg/L, this effect concentration is larger than the water solubility.