Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 297-474-6 | CAS number: 93572-43-1 A complex combination of hydrocarbons obtained by refining of crude oil. It consists predominantly of aromatics, naphthenics and paraffinics and produces a finished oil with a viscosity of 120 SUS at 100°F (23cSt at 40°C).
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Summary study report
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- ROBUST SUMMARY OF INFORMATION ON LUBRICATING OIL BASESTOCKS
- Author:
- American Petroleum Institute
- Year:
- 2 003
- Bibliographic source:
- ROBUST SUMMARY OF INFORMATION ON LUBRICATING OIL BASESTOCKS pag 30-31
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
- Deviations:
- not specified
- Principles of method if other than guideline:
- The test procedure was consistent with that given in OECD Guideline 404 (1981) except that the exposure period was 24 hours rather than the 4 hours recommended in the OECD protocol.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Distillates (petroleum), hydrotreated light naphthenic
- EC Number:
- 265-156-6
- EC Name:
- Distillates (petroleum), hydrotreated light naphthenic
- Cas Number:
- 64742-53-6
- IUPAC Name:
- 64742-53-6
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
Test system
- Type of coverage:
- other: see any other information on materials and methods
- Preparation of test site:
- not specified
- Vehicle:
- unchanged (no vehicle)
- Controls:
- not required
- Duration of treatment / exposure:
- 24 hours
- Observation period:
- 14 days
- Number of animals:
- 6
Results and discussion
In vivo
Results
- Irritation parameter:
- primary dermal irritation index (PDII)
- Basis:
- mean
- Time point:
- other: Results of the 24 and 72-hour readings were used to determine the Primary Irritation Index.
- Score:
- ca. 5.4
- Max. score:
- 5.8
- Reversibility:
- no data
Any other information on results incl. tables
| Observation period | Erythema Intact | Erythema Abraded | Edema Intact | Edema Abraded | Average Score |
| 24 hrs. | 2.3 | 2.3 | 2.7 | 2.7 | 5 |
| 72 hrs. | 3.0 | 3.0 | 2.5 | 3.0 | 5.8 |
| 96 hrs. | 2.7 | 2.8 | 2.7 | 3.0 | 5.6 |
| 7 days | 1.3 | 2.2 | 0.8 | 1.7 | 3.0 |
| 14 days | 0 | 0 | 0 | 0 | 0 |
Primary dermal irritation index: 5.4
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
