Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
Justification for type of information:
the substance is expected to have o Log Kow > 8 so that only QSAR calculation is included in the dossier.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
- Software tool(s) used including version: Calculated, KOWWIN programme v1.68; Estimation Programs Interface Suite™ for Microsoft® Windows, v 4.00. United States Environmental Protection Agency, Washington, DC, USA.
- Model(s) used:
- Model description: see field 'Justification for non-standard information', 'Attached justification' and/or 'Cross-reference'
- Justification of QSAR prediction: see field 'Justification for type of information', 'Attached justification' and/or 'Cross-reference'

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Substance %
Isopropyl Jojobate 30 – 40
Jojoba Alcohols 30 – 40
Jojoba Esters 30 – 40

Study design

Analytical method:
other: QSAR

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
ca. 12.86
Remarks on result:
not determinable because of methodological limitations

Applicant's summary and conclusion

Conclusions:
Calculated Partition Coefficient: 12.86