Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2 July 2007 to 16 July 2007
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
other: CIPAC Handbook; Vol. F, MT 157 - Water solubility; Vol. H, MT 181 Solubility in organic solvents
Deviations:
not specified
GLP compliance:
yes (incl. QA statement)
Remarks:
Ministerium für Umwelt und Naturschutz, Landwirtschaft und Verbraucherschutz, Düsseldorf, Nordrheim-Westfalen, Germany
Key result
Medium:
methanol
Solubility:
> 250 g/L
Temp.:
10 °C
Key result
Medium:
methanol
Solubility:
> 250 g/L
Temp.:
20 °C
Key result
Medium:
methanol
Solubility:
> 250 g/L
Temp.:
30 °C
Key result
Medium:
toluene
Solubility:
> 250 g/L
Temp.:
10 °C
Key result
Medium:
toluene
Solubility:
> 250 g/L
Temp.:
20 °C
Key result
Medium:
toluene
Solubility:
> 250 g/L
Temp.:
30
Test substance stable:
yes

Final Result

The solubility of the test item Chlorophene in methanol and in toluene at 10 °C, 20 °C and 30 °C were > 250 g/L (visually checked in preliminary tests). Therefore it was not necessary to determine the exact value of the solubility of the test item in a main test.

Individual Results

Preliminary test at 10 °C

Solvent

Initial weight

 

[g]

Volume of solvent

[mL]

Initial weight/volume

[g/L]

Conclusion (solubility,firstestimate)

Methanol

1.79

5

264*

>250g/L

Toluene

1.82

5

267*

>250g/L

*Calculation of the clear solution:

Initial weight / (Initial weight + Volume of solvent)

Example for Methanol:

1.79 g * 1000 mL / (1.79g + 5 mL) = 264 g/L

Preliminary test at 20 °C

Solvent

Initial weight

 

[g]

Volume of solvent

[mL]

Initial weight/volume

[g/L]

Conclusion (solubility,firstestimate)

Methanol

1.80

5

265*

>250g/L

Toluene

1.91

5

276*

>250g/L

Preliminary test at 30 °C

Solvent

Initial weight

 

[g]

Volume of solvent

[mL]

Initial weight/volume

[g/L]

Conclusion (solubility,firstestimate)

Methanol

1.80

5

265*

>250g/L

Toluene

1.91

5

276*

>250g/L

Description of key information

Solubility in methanol is > 250 g/L at 10 ºC, 20 ºC, and 30 ºC; solubility in toluene is > 250 g/L at 10 ºC, 20 ºC, 30 ºC (CIPAC MT 157, CIPAC MT 181).

Key value for chemical safety assessment

Additional information