Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
other: Secondary source
Adequacy of study:
supporting study
Study period:
Not available
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Insufficient information for an assessment of reliability.

Data source

Reference
Reference Type:
other: Secondary source
Title:
Unnamed
Year:
2011
Report date:
2011

Materials and methods

Principles of method if other than guideline:
Not available
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
2-ethylbutyric acid
EC Number:
201-796-4
EC Name:
2-ethylbutyric acid
Cas Number:
88-09-5
Molecular formula:
C6H12O2
IUPAC Name:
2-ethylbutyric acid
Test material form:
not specified

Test animals / tissue source

Species:
rabbit

Test system

Vehicle:
not specified
Details on study design:
Open irritation test

Results and discussion

In vivo

Results
Irritation parameter:
other: Eye irritation
Reversibility:
not specified
Remarks on result:
positive indication of irritation
Remarks:
Severe

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Conclusions:
Severe eye irritation was observed from exposure to 2-ethylbutyric acid, however, reversibility was not specified.

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