Registration Dossier
Registration Dossier
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EC number: 201-796-4 | CAS number: 88-09-5
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- other: Secondary source
- Adequacy of study:
- supporting study
- Study period:
- Not available
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Insufficient information for an assessment of reliability.
Data source
Reference
- Reference Type:
- other: Secondary source
- Title:
- Unnamed
- Year:
- 2 011
- Report date:
- 2011
Materials and methods
- Principles of method if other than guideline:
- Not available
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2-ethylbutyric acid
- EC Number:
- 201-796-4
- EC Name:
- 2-ethylbutyric acid
- Cas Number:
- 88-09-5
- Molecular formula:
- C6H12O2
- IUPAC Name:
- 2-ethylbutyric acid
- Test material form:
- not specified
Constituent 1
Test animals / tissue source
- Species:
- rabbit
Test system
- Vehicle:
- not specified
- Details on study design:
- Open irritation test
Results and discussion
In vivo
Results
- Irritation parameter:
- other: Eye irritation
- Reversibility:
- not specified
- Remarks on result:
- positive indication of irritation
- Remarks:
- Severe
Applicant's summary and conclusion
- Interpretation of results:
- study cannot be used for classification
- Conclusions:
- Severe eye irritation was observed from exposure to 2-ethylbutyric acid, however, reversibility was not specified.
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