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EC number: 229-175-3 | CAS number: 6422-83-9
Table 1: Incidence of immobility in the additional range-ﬁnding test (flow-through):
Concentration Test substance; Target/Acutal (mg/L)
Number Daphnia exposed
Response at 24 h
Response at 48 h
Table 2: Measured and average measured concentrations per test group (final test)
Concentration Target (mg/L)
Measured T=0 (mg/L)
Measured T=48 h (mg/L)
Mean Measured (mg/L)
Table 3:Acute immobilisation of Daphnia after 24 and 48 hours in the final EC50 study.
Concentration Test substance; Target/Mean (mg/L)
*Inadvertently 4 instead of 5 Daphnids were exposed
- short-term toxicity to aquatic invertebrates: according to OECD TG 202 (adopted April 4th, 1984); RL 1; GLP; test with Daphnia magna 48 h EC50 = 591.4 µg/L
The 48-hr-acute toxicity of 2,4-Bismaleimidotoluene to Daphnia magna was studied under flow-through conditions according to OECD Guideline 202 (2004). Daphnids were exposed to control and test chemical at nominal concentrations of 0.10, 0.22, 0.46, 1.0 and 2.2 mg a.i./L (corresponding to 0.059, 0.085, 0.19, 0.31 and 0.82 mg/L mean measured concentrations) in tap water for 48 h. Mortality/immobilization was observed daily, pH was recorded at the beginning and at the end of the test and temperature was measured continuously. 2,4-Bismaleimidotoluene did not induce acute lmmobilisation of Daphnia magna at or below nominal concentrations of 1.0 mg/l, corresponding to a mean exposure concentration of 0.31 mg/l under flow-through test conditions (NOEC). The 48-hour EC50 was determined to be 0.59 mg a.i./L (95% confidence limits: 0.52 and 0.72 mg/L).
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