Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Hydrolysis:

- OECD guideline study (111), GLP, moderate to fast hydrolysis under test conditions

Additional information

Hydrolysis:

In a study conducted according to OECD guideline 111 (2004), 30 mg/L of the test substance were dissolved in three buffers, pH 4, 7 and 9 and incubated at different temperatures (5, 10, 20, 30, and 50°C). The test item showed a moderate hydrolysis rate (2.4 h ≤ t1/2 ≤ 30 d) for pH 4 at 20 and 30 °C as well as for pH 7 at 20 °C and a fast hydrolysis rate (t1/2 ≤ 2.4 h) for the remaining test conditions (pH 4 at 50 °C, pH 7 at 30 and 50 °C as well as for pH 9 at 5, 10 and 20°C), with the higher half-lives at acidic conditions. Major transformation products were observed at all pH values and temperatures.