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EC number: 229-175-3 | CAS number: 6422-83-9
The measured concentrations of the test item at the start of the exposure were in the range of 106 to 107% of the nominal values. After 24 hours of the exposure, the highest concentration of the test item was < LOQ of the nominal values. Therefore it can be considered that the concentrations of the test item at the end of the exposure were below LOQ, too.
Table 1: Nominal and measured concentrations of the test item:
Start of the exposure
Nominal test item concentration
Table 2: Evaluation after 72h:
Initially measured test item concentration
Growth rate [d-1]
Inhibition of growth rate [%]
Inhibition of yield[%]
(0.100 ml- DMF/L)
Table 3: Cell Densities:
Initially measured test item concentration[mg/L]
Cell density [cells/mL]
- OECD guideline study (201, adopted 2011), fresh water green alga Desmodesmus subspicatus was exposed to nominal concentrations of 0.625, 1.25, 2.50, 5.00, 10.0 mg/L corresponding to initial measured concentrations of 0.667, 1.33, 2.64, 5.28, 10.6 mg/L for 72h under static conditions. EC50 = > 10.6 mg/L, EC10 = >10.6 mg/L and NOEC (growth) = 2.64 mg/L
In a study conducted according to OECD TG 201 freshwater green alga Desmodesmus subspicatus was exposed to 2,4 -Bismaleimidotoluene at nominal concentrations of 0.625, 1.25, 2.50, 5.00, 10.0 mg/L corresponding to initial measured concentrations of 0.667, 1.33, 2.64, 5.28, 10.6 mg/L for 72h under static conditions.
2,4-Bismaleimidotoluene was found to inhibit the growth rate of the freshwater green alga Desmodesmus subspicatus after 72 hours. The EC50-values with 95 % confidence intervals for both inhibition of growth rate (ErC50) and yield (EyC50) after 72 hours were > 10.6 mg/L, respectively. The EC10-values with 95 % confidence intervals for inhibition of growth rate (ErC10) and yield (EyC10) after 72 hours were > 10.6 mg/L and < 0.667 mg/L, respectively. The NOEC-values for both inhibition of growth rate and yield after 72 hours were 2.64 and < 0.667 mg/L, respectively.
All effect levels are given based on the initially measured test item concentration of 2,4-Bismaleimidotoluene.
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