Registration Dossier

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
3 July 2017 to 18 July 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report Date:
2017

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
not specified
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
not specified
Qualifier:
according to
Guideline:
EPA OPPTS 830.7200 (Melting Point / Melting Range)
Deviations:
not specified
GLP compliance:
yes (incl. certificate)
Remarks:
Health Care Inspectorate of the Ministry of Health, Welfare and Sport; Utrecht, The Netherlands
Type of method:
differential scanning calorimetry

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Melting / freezing point
Melting / freezing pt.:
132.3 °C
Decomp. temp.:
> 275 °C

Any other information on results incl. tables

Preliminary Test

The TGA curve of the test item started at 400 °C, beyond this temperature the weight of the sample decreased significantly. At 476 °C, the sample weight had decreased by 25%.

After the experiment, a brown molten residue remained in the sample container (original colour: white). The change of the colour indicated reaction and/or decomposition of the test item.

Main Study

An endothermic peak in the DSC curve was observed between 100 °C and 150 °C. The extrapolated onset temperature of the peak was 131.225 °C. The endothermic effect was most likely obtained due to melting of the test item. From 275 °C a small exothermic effect was observed. The effect was probably obtained due to reaction and/or decomposition of the test item.

After the experiment, a light yellow molten residue remained in the sample container (original colour: white). The change of the colour indicated reaction and/or decomposition of the test item. Based on this visual observation, it was found that the test item had molten and the change of the colour demonstrated reaction and/or decomposition of the test item.

In order to investigate the melting peak, Experiment 2 was stopped directly after the melting peak. The extrapolated onset temperature was 133.416 °C. After the experiment, a colourless molten residue remained in the sample container. Based on this visual observation, it demonstrated that melting was the reason for the endothermic effect.

The melting temperature was determined as the mean melting temperature of Experiment 1 (131.225 °C) and Experiment 2 (133.416 °C).

Conclusion

The melting and boiling temperature of 4,4'-[isopropylidenebis(4,1-phenyleneoxy)]dianiline were determined by DSC.

The melting temperature of the test item was 132.3 °C (405.5K)

Reaction and/or decomposition of the test item was observed during DSC experiment at temperatures of > 275 °C (> 548K). Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test item has no boiling temperature.

Applicant's summary and conclusion