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EC number: 259-709-0 | CAS number: 55566-30-8
Biodegradation in water and sediment: simulation tests
Administrative data
Link to relevant study record(s)
Description of key information
Simulation study, EPA Guideline N 162-4, GLP, key study, validity 1,
aerobic conditions:
THPS is considered as rapidely degradable with an half-life for mineralisation (as CO2 evolved) of 2 days at 25°C.
Simulation study, EPA Guideline N 162-3, GLP, key study, validity
1, anaerobic conditions:
THPS is considered as rapidely degradable with an half-life for mineralisation (as CO2 evolved) of 14 days at 25°C.
Aerobic data are considered relevant for risk assessment and classification purposes.
(For more details please read CSR available in section 13).
Key value for chemical safety assessment
- Half-life in freshwater:
- 2 d
- at the temperature of:
- 25 °C
- Half-life in freshwater sediment:
- 14 d
- at the temperature of:
- 25 °C
Additional information
Two studies of relability 1 are available to assess the biodegradation of the active substance THPS in water/sediment systems using low THPS concentrations. These studies were performed on the THPS in solution, under aerobic and anaerobic conditions, and have been defined as key studies.
The first study (Gorman, 1996) has been performed in aerobic conditions. The results of this study show that THPS is readily biodegradable as the pass level of 60 % biodegradation (expressed as %CO2 evolved) was reached within 10 days. THPS was not detected in any of the water layer samples. The major degradation product THPO was only detected at a level > 10 % in the day 0 water layer sample. A mineralisation half-life of 2 days (based on CO2 evolution) at 25°C in freshwater has been estimated for risk assessment purposes.
The second study (Gorman, 1997) has been performed in anaerobic conditions. The results of this study show that THPS is biodegradable in anaerobic environments. Approximately 60 % of the test substance was mineralised within 30 days, and mineralisation was greater than 80 % by one year. From the % CO2 evolution curve, a rough half-life of 14 days at 25 °C has been estimated for risk assessment purposes.
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