Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-712-4 | CAS number: 124-76-5
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Reference
- Reference Type:
- publication
- Title:
- A toxicologic and dermatologic assessment of cyclic and non-cyclic terpene alcohols when used as fragrance ingredients
- Author:
- Belsito D
- Year:
- 2 008
- Bibliographic source:
- Food and Chemical Toxicology 46, S1-S71
Materials and methods
- Principles of method if other than guideline:
- No data provided on the method.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Exo-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol
- EC Number:
- 204-712-4
- EC Name:
- Exo-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol
- Cas Number:
- 124-76-5
- Molecular formula:
- C10H18O
- IUPAC Name:
- 1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol
- Test material form:
- solid
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
- No. of animals per sex per dose:
- 5
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- other: Not classified (CLP Regulation EC no. 1272/2008)
- Conclusions:
- The acute dermal LD50 value of the test substance was >5000 mg/kg bw in rabbits.
- Executive summary:
The acute dermal LD50 value of the test substance was >5000 mg/kg bw in rabbits.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
