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Toxicity to soil microorganisms

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Key value for chemical safety assessment

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In accordance with Column 2 of REACH Annex IX toxicity testing with terrestrial microorganisms (required in Section 9.4.2) is not needed as the chemical safety assessment according to Annex I indicates that this is not necessary.

Moreover, considerable technical difficulties would be expected in the conduct of such a test, due to the very rapid biotic removal of the substance from the test system. Please refer to discussion of the long-term aquatic invertebrate and fish studies, and evidence of rapid removal in non-sterilised soils during method development for the adsorption/desorption study with natural soils , carried out with the close structural analogue decan-1-ol, in the environmental fate section.

The terrestrial chemical safety assessment has been conducted using the Equilibrium Partitioning method (EQPM). It is recognised that the aquatic PNEC used in the EQPM does not take into account any indicator for effects in aquatic microorganisms. However, analogous alcohols within the Category are very rapidly biodegradable and show no significant inhibitory effects on respiration of activated sludge or specific microbial strains relevant to WWTP, at or above the limit of solubility (based on inhibition tests and lack of toxicity in ready biodegradability test). A lack of toxicity to soil microbiota was suggested by a recent experimental finding associated with a recent study of adsorption/desorption (OECD 106, Wildlife International, 2015) using decan-1-ol. Significant technical difficulties were encountered during method development for this study using natural standard soils, in that it was not possible to detect sufficient substance and establish equilibrium in non-sterilised soil samples. Therefore it is unlikely that the PNECterrestrial based on aquatic ecotoxicity test results would not be protective for terrestrial microorganisms. The chemical safety assessment using EQPM does not suggest any unacceptable risks for the terrestrial compartment.

Therefore, further toxicity testing with terrestrial microorganisms does not need to be conducted.