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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Remarks:
Peer-reviewed assessment report (attached in section 13)
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient - Shake Flask Method)
GLP compliance:
yes
Type of method:
flask method
Partition coefficient type:
octanol-water
Specific details on test material used for the study:
Purity: 99.2%
Type:
log Pow
Partition coefficient:
3.39
pH:
7
Remarks on result:
other: temperature not specified
Type:
log Pow
Partition coefficient:
3.18
pH:
5
Remarks on result:
other: temperature not specified
Type:
log Pow
Partition coefficient:
3.19
pH:
9
Remarks on result:
other: temperature not specified
Conclusions:
As information was provided via a peer-reviewed assessment report, it can be considered as sufficiently reliable. The measured log Pow of ethoxyquin is 3.18, 3.39 and 3.19, respectively at pH 5, 7 and 9.
Executive summary:

A study according to EU Method A.8 (GLP) has been conducted to determine the partition coefficient. The measured log Pow of ethoxyquin is 3.18, 3.39 and 3.19, respectively at pH 5, 7 and 9.

Description of key information

The measured log Pow of ethoxyquin is 3.18, 3.39 and 3.19, respectively at pH 5, 7 and 9.

Key value for chemical safety assessment

Log Kow (Log Pow):
3.39

Additional information