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Environmental fate & pathways

Biodegradation in water and sediment: simulation tests

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
biodegradation in water and sediment: simulation tests
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data is from computational model developed by USEPA
Justification for type of information:
Data is from computational model developed by USEPA
Qualifier:
according to guideline
Guideline:
other: Modeling database
Principles of method if other than guideline:
Fugacity Model by EPI Suite estimation database
GLP compliance:
not specified
Specific details on test material used for the study:
- Name of test material (as cited in study report): 1-methylpiperidin-4-ol
- Molecular formula: C6H13NO
- Molecular weight: 115.175 g/mol
- Substance type: Organic
- Physical state: Liquid
Radiolabelling:
not specified
Oxygen conditions:
other: estimation
Inoculum or test system:
not specified
Parameter followed for biodegradation estimation:
test mat. analysis
Compartment:
other: water, material (mass) balance
% Recovery:
34.9
Compartment:
other: sediment, material (mass) balance
% Recovery:
0.07
Key result
% Degr.:
50
Parameter:
other: Half life in water
Sampling time:
15 d
Remarks on result:
other: Other details not known
Key result
% Degr.:
50
Parameter:
other: Half-life in sediment
Sampling time:
135 d
Remarks on result:
other: Other details not known
Key result
Compartment:
water
DT50:
15 d
Type:
other: estimation
Temp.:
25 °C
Remarks on result:
other: Other details not known
Key result
Compartment:
sediment
DT50:
135 d
Type:
other: estimation
Temp.:
25 °C
Remarks on result:
other: Other details not known
Transformation products:
not specified
Evaporation of parent compound:
not specified
Volatile metabolites:
not specified
Residues:
not specified
Validity criteria fulfilled:
not specified
Conclusions:
Estimated half life of 4-Piperidinol, 1-methyl- in water was 15 days (360 h) and in sediment estimated to be 135 days (3240 h).
Executive summary:

Estimation Programs Interface (EPI) Suite (2016) prediction model was run to predict the half-life in water and sediment for the test compound 4-Piperidinol, 1-methyl- (CAS No. 106 -52 -5). Half life period of 4-Piperidinol, 1-methyl- in water isestimated to be 15 days (360 hrs), while in sediment

it is 135 days (3240 hrs). Based on these half life values of 4 -Piperidinol, 1 -methyl-, it is concluded that the chemical is not persistent in water but persistent in sediment.

Description of key information

Estimated half life of 4-Piperidinol, 1-methyl- in water was 15 days (360 h) and in sediment estimated to be 135 days (3240 h).

Key value for chemical safety assessment

Half-life in freshwater:
15 d
at the temperature of:
25 °C
Half-life in freshwater sediment:
135 d
at the temperature of:
25 °C

Additional information

Estimation Programs Interface (EPI) Suite (2016) prediction model was run to predict the half-life in water and sediment for the test compound 4-Piperidinol, 1-methyl- (CAS No. 106 -52 -5). Half life period of 4-Piperidinol, 1-methyl- in water isestimated to be 15 days (360 hrs), while in sediment it is 135 days (3240 hrs). Based on these half life values of 4 -Piperidinol, 1 -methyl-, it is concluded that the chemical is not persistent in water but persistent in sediment.