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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Repeated dose toxicity: oral

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Administrative data

Endpoint:
chronic toxicity: oral
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Justification for type of information:
The justification document on the read across category approach is included in IUCLID section 13.

Data source

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzenesulfonic acid, 4-C20-24 (even numbered) sec-alkyl derivs.
EC Number:
701-015-1
Cas Number:
2156592-72-0
Molecular formula:
C9H12SO3(CH2)n n=17-21
IUPAC Name:
Benzenesulfonic acid, 4-C20-24 (even numbered) sec-alkyl derivs.
Test material form:
other: liquid
Details on test material:
The test substance is a brown viscous liquid with sulfurous odor.

Results and discussion

Effect levels

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Dose descriptor:
NOAEL
Effect level:
40 mg/kg bw/day (nominal)
Based on:
test mat.
Sex:
male/female
Basis for effect level:
other: increased weight of cecum and slight degeneration of the renal tubes
Dose descriptor:
LOAEL
Effect level:
115 mg/kg bw/day (nominal)
Based on:
test mat.
Sex:
male/female
Basis for effect level:
other: increased weight of cecum and slight degeneration of the renal tubes

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion

Conclusions:
The test substance is considered to have an NOAEL of 40 mg/kg bw and LOAEL 115 mg/kg bw. The substance is not to be classified as STOT RE according to CLP Regulation.