Registration Dossier
Registration Dossier
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EC number: 701-015-1 | CAS number: 2156592-72-0
Endpoint summary
Administrative data
Description of key information
No terrestrial toxicity study with the target substance is available. Data generated with the category substance LABS Na was considered pitoval to this endpoint.
A review of studies on the toxicity of LAS to soil macro-organisms and terrestrial plants was done in order to determine a predicted level of no adverse effects (PNEC) in soil (Jensen at al. 2007). Nine invertebrate studies and 12 plants studies were used to calculate the PNEC. In all the plant experiments, LAS was added as an aqueous solution, and the most sensitive endpoint, growth, was used in calculated the PNEC. In cases where an NOEC or EC10 value was not reported, the original data or graphical estimations were used to calculate the EC10 value. This was considered more appropriate than using an arbitrary extrapolation factor. Invertebrate data was based on 9 chronic studies. In cases where there was more than one study on a particular species, a geometric mean of the data was used. The data for both sets of studies were merged as the sensitivity of both types of species were similar. This was confirmed by the Kolmogorov-Smirnov test. The species sensitivity distribution was then calculated. From this, the concentration that would exceed NOEC or EC10 for 5% of species was calculated (HC5). Based on this information, the HC5 was determined to be 35.3 mg/kg soil. The 95% confidence interval was 18.6-50.0 mg/kg. The PNEC for soil is therefore 35 mg/kg.Additional information
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