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Endpoint summary

Description of key information

Short term toxicity tests are available for all the three tropic levels (fish, invertebrates and aquatic plants). In a 48 h acute fish toxicity test, the test substance FAT40069was observed to have 48 h LC50 to Rainbow trout 45 mg/L. Similarly in as study conducted according to OECD Guideline 202, the 48 h EC50 value of the test substance FAT 40069 toDaphnia magna was determined to be >100 mg/L. The NOEC value for 48 hours was determined to be 100 mg/L. Due to intrinsic properties of the substance, the test to determine the acute toxicity to aquatic algae and cyanobacteria cannot be performed. The dark coloration of the test medium and reduced light intensity in the medium modifying the conditions of test. Hence, to determine the toxicity to the aquatic plant Lemna minor, a semi-static growth inhibition test was performed. In a GLP-compliant OECD Guideline 221 study, Lemna gibba (Duckweed) exposed to the test item FAT 40069 recorded: 7 day ErC50 based upon the frond number is >100 mg/L. 7 day EyC50 based upon the frond numbers is >100 mg/L. 7 day ErC50 based upon the frond dry weight is >100 mg/L. 7 day EyC50 based upon the frond dry weight is >100 mg/L.The NOEC was 0.64 mg/L and the LOEC was >100 mg /L.Therefore, it can be concluded that there were no toxic effects at saturation. A key toxicity study of FAT 40069/A to activated sludge was determined in a 3-hours respiration inhibition test according to EU Method B-10.The IC50 (3 h) of the test substance FAT 40069/A is greater than 300 mg/L.