Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 235-008-5 | CAS number: 12054-48-7
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Secondary source
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Technical Reports
- Author:
- RCC NOTOX B.V.
- Year:
- 1 988
- Bibliographic source:
- RCC Notox, Technical Report No. 1074; cited in RTECS, 2000
Materials and methods
- Principles of method if other than guideline:
- Study to assess the acute inhalative toxicity in rats.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Nickel dihydroxide
- EC Number:
- 235-008-5
- EC Name:
- Nickel dihydroxide
- Cas Number:
- 12054-48-7
- Molecular formula:
- H2NiO2
- IUPAC Name:
- nickel(2+) dihydroxide
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation
- Type of inhalation exposure:
- not specified
- Vehicle:
- other: no data
- Analytical verification of test atmosphere concentrations:
- not specified
- Duration of exposure:
- 4 h
- Concentrations:
- no data
- No. of animals per sex per dose:
- no data
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- 1.2 mg/L air
- Exp. duration:
- 4 h
- Remarks on result:
- other: original data: 1200mg/m3
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
